Package: SingleArmMRCT
Type: Package
Title: Regional Consistency Probability for Single-Arm Multi-Regional
        Clinical Trials
Version: 0.1.1
Authors@R: person(
    given  = "Gosuke",
    family = "Homma",
    role   = c("aut", "cre"),
    email  = "my.name.is.gosuke@gmail.com"
  )
Description: Provides functions to calculate and visualise the Regional
        Consistency Probability (RCP) for single-arm multi-regional
        clinical trials (MRCTs) using the Effect Retention Approach
        (ERA). Six endpoint types are supported: continuous, binary,
        count (negative binomial), time-to-event via hazard ratio,
        milestone survival, and restricted mean survival time (RMST).
        For each endpoint, both a closed-form (or semi-analytical)
        solution and a Monte Carlo simulation approach are implemented.
        Two consistency evaluation methods are available: Method 1
        (effect retention in Region 1 relative to the overall
        population) and Method 2 (simultaneous positive effect across
        all regions). Plotting functions generate faceted
        visualisations of RCP as a function of the regional allocation
        proportion, overlaying formula and simulation results for
        direct comparison. The methodology follows the Japanese MHLW
        guidelines for MRCTs. Abbreviations used: RCP (Regional
        Consistency Probability), MRCT (Multi-Regional Clinical Trial),
        RMST (Restricted Mean Survival Time), MHLW (Ministry of Health,
        Labour and Welfare).
License: MIT + file LICENSE
Encoding: UTF-8
Language: en-GB
Roxygen: list(markdown = TRUE)
RoxygenNote: 7.3.3
Depends: R (>= 4.1.0)
Imports: stats, ggplot2 (>= 3.4.0)
Suggests: testthat (>= 3.0.0), knitr, rmarkdown
VignetteBuilder: knitr
URL: https://gosukehommaEX.github.io/SingleArmMRCT/,
        https://github.com/gosukehommaEX/SingleArmMRCT
BugReports: https://github.com/gosukehommaEX/SingleArmMRCT/issues
Config/testthat/edition: 3
Repository: https://gosukehommaex.r-universe.dev
Date/Publication: 2026-04-02 00:44:48 UTC
RemoteUrl: https://github.com/gosukehommaex/singlearmmrct
RemoteRef: HEAD
RemoteSha: 809cad455aef032121357d04a3d20dcea3da9e93
NeedsCompilation: no
Packaged: 2026-07-07 06:34:01 UTC; root
Author: Gosuke Homma [aut, cre]
Maintainer: Gosuke Homma <my.name.is.gosuke@gmail.com>