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# CITATION file created with {cffr} R package
# See also: https://docs.ropensci.org/cffr/
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cff-version: 1.2.0
message: 'To cite package "SingleArmMRCT" in publications use:'
type: software
license: MIT
title: 'SingleArmMRCT: Regional Consistency Probability for Single-Arm Multi-Regional
  Clinical Trials'
version: 0.1.1
doi: 10.32614/CRAN.package.SingleArmMRCT
abstract: 'Provides functions to calculate and visualise the Regional Consistency
  Probability (RCP) for single-arm multi-regional clinical trials (MRCTs) using the
  Effect Retention Approach (ERA). Six endpoint types are supported: continuous, binary,
  count (negative binomial), time-to-event via hazard ratio, milestone survival, and
  restricted mean survival time (RMST). For each endpoint, both a closed-form (or
  semi-analytical) solution and a Monte Carlo simulation approach are implemented.
  Two consistency evaluation methods are available: Method 1 (effect retention in
  Region 1 relative to the overall population) and Method 2 (simultaneous positive
  effect across all regions). Plotting functions generate faceted visualisations of
  RCP as a function of the regional allocation proportion, overlaying formula and
  simulation results for direct comparison. The methodology follows the Japanese MHLW
  guidelines for MRCTs. Abbreviations used: RCP (Regional Consistency Probability),
  MRCT (Multi-Regional Clinical Trial), RMST (Restricted Mean Survival Time), MHLW
  (Ministry of Health, Labour and Welfare).'
authors:
- family-names: Homma
  given-names: Gosuke
  email: my.name.is.gosuke@gmail.com
repository: https://gosukehommaex.r-universe.dev
repository-code: https://github.com/gosukehommaEX/SingleArmMRCT
commit: 809cad455aef032121357d04a3d20dcea3da9e93
url: https://gosukehommaEX.github.io/SingleArmMRCT/
date-released: '2026-04-02'
contact:
- family-names: Homma
  given-names: Gosuke
  email: my.name.is.gosuke@gmail.com