{
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  "Package": "SingleArmMRCT",
  "Type": "Package",
  "Title": "Regional Consistency Probability for Single-Arm Multi-Regional\nClinical Trials",
  "Version": "0.1.1",
  "Authors@R": "person(\ngiven  = \"Gosuke\",\nfamily = \"Homma\",\nrole   = c(\"aut\", \"cre\"),\nemail  = \"my.name.is.gosuke@gmail.com\"\n)",
  "Description": "Provides functions to calculate and visualise the Regional\nConsistency Probability (RCP) for single-arm multi-regional\nclinical trials (MRCTs) using the Effect Retention Approach\n(ERA). Six endpoint types are supported: continuous, binary,\ncount (negative binomial), time-to-event via hazard ratio,\nmilestone survival, and restricted mean survival time (RMST).\nFor each endpoint, both a closed-form (or semi-analytical)\nsolution and a Monte Carlo simulation approach are implemented.\nTwo consistency evaluation methods are available: Method 1\n(effect retention in Region 1 relative to the overall\npopulation) and Method 2 (simultaneous positive effect across\nall regions). Plotting functions generate faceted\nvisualisations of RCP as a function of the regional allocation\nproportion, overlaying formula and simulation results for\ndirect comparison. The methodology follows the Japanese MHLW\nguidelines for MRCTs. Abbreviations used: RCP (Regional\nConsistency Probability), MRCT (Multi-Regional Clinical Trial),\nRMST (Restricted Mean Survival Time), MHLW (Ministry of Health,\nLabour and Welfare).",
  "License": "MIT + file LICENSE",
  "Encoding": "UTF-8",
  "Language": "en-GB",
  "Roxygen": "list(markdown = TRUE)",
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  "URL": "https://gosukehommaEX.github.io/SingleArmMRCT/,\nhttps://github.com/gosukehommaEX/SingleArmMRCT",
  "BugReports": "https://github.com/gosukehommaEX/SingleArmMRCT/issues",
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  "Repository": "https://gosukehommaex.r-universe.dev",
  "Date/Publication": "2026-04-02 00:44:48 UTC",
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    "Date": "2026-05-08 09:20:49 UTC",
    "User": "root"
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  "Author": "Gosuke Homma [aut, cre]",
  "Maintainer": "Gosuke Homma <my.name.is.gosuke@gmail.com>",
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  "_topics": [
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    "plot_rcp1armContinuous",
    "plot_rcp1armCount",
    "plot_rcp1armHazardRatio",
    "plot_rcp1armMilestoneSurvival",
    "plot_rcp1armRMST",
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    "rcp1armMilestoneSurvival",
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    {
      "page": "plot_rcp1armBinary",
      "title": "Plot Regional Consistency Probability for Single-Arm MRCT (Binary Endpoint)",
      "topics": [
        "plot_rcp1armBinary"
      ]
    },
    {
      "page": "plot_rcp1armContinuous",
      "title": "Plot Regional Consistency Probability for Single-Arm MRCT (Continuous Endpoint)",
      "topics": [
        "plot_rcp1armContinuous"
      ]
    },
    {
      "page": "plot_rcp1armCount",
      "title": "Plot Regional Consistency Probability for Single-Arm MRCT (Count Endpoint)",
      "topics": [
        "plot_rcp1armCount"
      ]
    },
    {
      "page": "plot_rcp1armHazardRatio",
      "title": "Plot Regional Consistency Probability for Single-Arm MRCT (Hazard Ratio Endpoint)",
      "topics": [
        "plot_rcp1armHazardRatio"
      ]
    },
    {
      "page": "plot_rcp1armMilestoneSurvival",
      "title": "Plot Regional Consistency Probability for Single-Arm MRCT (Milestone Survival Endpoint)",
      "topics": [
        "plot_rcp1armMilestoneSurvival"
      ]
    },
    {
      "page": "plot_rcp1armRMST",
      "title": "Plot Regional Consistency Probability for Single-Arm MRCT (RMST Endpoint)",
      "topics": [
        "plot_rcp1armRMST"
      ]
    },
    {
      "page": "print.rcp1armBinary",
      "title": "Print Method for rcp1armBinary Objects",
      "topics": [
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      ]
    },
    {
      "page": "print.rcp1armContinuous",
      "title": "Print Method for rcp1armContinuous Objects",
      "topics": [
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      ]
    },
    {
      "page": "print.rcp1armCount",
      "title": "Print Method for rcp1armCount Objects",
      "topics": [
        "print.rcp1armCount"
      ]
    },
    {
      "page": "print.rcp1armHazardRatio",
      "title": "Print Method for rcp1armHazardRatio Objects",
      "topics": [
        "print.rcp1armHazardRatio"
      ]
    },
    {
      "page": "print.rcp1armMilestoneSurvival",
      "title": "Print Method for rcp1armMilestoneSurvival Objects",
      "topics": [
        "print.rcp1armMilestoneSurvival"
      ]
    },
    {
      "page": "print.rcp1armRMST",
      "title": "Print Method for rcp1armRMST Objects",
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      ]
    },
    {
      "page": "rcp1armBinary",
      "title": "Regional Consistency Probability for Single-Arm MRCT (Binary Endpoint)",
      "topics": [
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      ]
    },
    {
      "page": "rcp1armContinuous",
      "title": "Regional Consistency Probability for Single-Arm MRCT (Continuous Endpoint)",
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      ]
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