Package: bbssr
Type: Package
Title: Blinded Sample Size Re-Estimation for Binary Endpoints
Version: 1.0.2
Date: 2025-06-14
Authors@R: person("Gosuke", "Homma", email = "my.name.is.gosuke@gmail.com", 
                  role = c("aut", "cre"))
Description: Provides comprehensive tools for blinded sample size
        re-estimation (BSSR) in two-arm clinical trials with binary
        endpoints. Unlike traditional fixed-sample designs, BSSR allows
        adaptive sample size adjustments during trials while
        maintaining statistical integrity and study blinding.
        Implements five exact statistical tests: Pearson chi-squared,
        Fisher exact, Fisher mid-p, Z-pooled exact unconditional, and
        Boschloo exact unconditional tests. Supports restricted,
        unrestricted, and weighted BSSR approaches with exact Type I
        error control. Statistical methods based on Mehrotra et al.
        (2003) <doi:10.1111/1541-0420.00051> and Kieser (2020)
        <doi:10.1007/978-3-030-49528-2_21>.
License: MIT + file LICENSE
URL: https://github.com/gosukehommaEX/bbssr
BugReports: https://github.com/gosukehommaEX/bbssr/issues
Depends: R (>= 3.5.0)
Imports: fpCompare, stats
Suggests: testthat (>= 3.0.0), knitr, rmarkdown, dplyr, ggplot2,
        tibble, tidyr, Exact, exact2x2, microbenchmark
VignetteBuilder: knitr
Encoding: UTF-8
RoxygenNote: 7.3.2
Roxygen: list(markdown = TRUE)
Config/testthat/edition: 3
Repository: https://gosukehommaex.r-universe.dev
Date/Publication: 2025-06-18 21:37:38 UTC
RemoteUrl: https://github.com/gosukehommaex/bbssr
RemoteRef: HEAD
RemoteSha: e7021ecf088e6ca25228d9df9816ec5bd8e5b7cd
NeedsCompilation: no
Packaged: 2026-07-18 06:47:16 UTC; root
Author: Gosuke Homma [aut, cre]
Maintainer: Gosuke Homma <my.name.is.gosuke@gmail.com>