Package: simFastBOIN Type: Package Title: Fast Bayesian Optimal Interval Design for Phase I Dose-Finding Trials Version: 1.3.2 Date: 2025-12-06 Authors@R: person(given = "Gosuke", family = "Homma", role = c("aut", "cre"), email = "my.name.is.gosuke@gmail.com", comment = c(ORCID = "0000-0002-6854-5627")) Description: Conducting Bayesian Optimal Interval (BOIN) design for phase I dose-finding trials. 'simFastBOIN' provides functions for pre-computing decision tables, conducting trial simulations, and evaluating operating characteristics. The package uses vectorized operations and the Iso::pava() function for isotonic regression to achieve efficient performance while maintaining full compatibility with BOIN methodology. Version 1.3.2 adds p_saf and p_tox parameters for customizable safety and toxicity thresholds. Version 1.3.1 fixes Date field. Version 1.2.1 adds comprehensive 'roxygen2' documentation and enhanced print formatting with flexible table output options. Version 1.2.0 integrated C-based PAVA for isotonic regression. Version 1.1.0 introduced conservative MTD selection (boundMTD) and flexible early stopping rules (n_earlystop_rule). Methods are described in Liu and Yuan (2015) . License: MIT + file LICENSE Imports: knitr, kableExtra, Iso, stats Suggests: testthat (>= 3.0.0), rmarkdown Encoding: UTF-8 Roxygen: list(markdown = TRUE) RoxygenNote: 7.3.3 Language: en-US URL: https://github.com/gosukehommaEX/simFastBOIN BugReports: https://github.com/gosukehommaEX/simFastBOIN/issues Config/testthat/edition: 3 VignetteBuilder: knitr Config/pak/sysreqs: cmake libfontconfig1-dev libfreetype6-dev libfribidi-dev make libharfbuzz-dev libicu-dev libpng-dev libuv1-dev libxml2-dev Repository: https://gosukehommaex.r-universe.dev Date/Publication: 2025-12-11 14:07:43 UTC RemoteUrl: https://github.com/gosukehommaex/simfastboin RemoteRef: HEAD RemoteSha: b403d90c714f6a545dd379d2ab7e515c6403c13d NeedsCompilation: no Packaged: 2026-07-16 07:22:03 UTC; root Author: Gosuke Homma [aut, cre] (ORCID: ) Maintainer: Gosuke Homma